Phylogenetic relationships between hats the extinct woolly mammoth (Mammuthus primigenius), and the Asian (Elephas maximus) and African savanna (Loxodonta africana) elephants remain unresolved.Here, we report the sequence of the complete mitochondrial genome (16,842 base pairs) of a woolly mammoth extracted from permafrost-preserved remains from th
Assessing sterility techniques in bronchodilator responsiveness testing by practicing allergists in North America
Background: The American Thoracic Society has published general guidelines for sterility when testing for bronchodilator responsiveness.However, the extent to which practicing allergists implement sterility measures is currently unknown.Objective: This study aims to understand the adherence to the American Thoracic Society guidelines for sterility
Specialized neurons in the right habenula mediate response to aversive olfactory cues
Hemispheric specializations are well studied at the functional level but less is known about the underlying neural mechanisms.We identified a small cluster of cholinergic neurons in the dorsal habenula (dHb) of zebrafish, defined by their expression of the lecithin retinol acyltransferase domain containing 2 a (lratd2a) gene and their efferent conn
Incorporating hematopoietic stem-cell transplantation after second-line carfilzomib-lenalidomide-dexamethasone (KRd)
Background: Traditionally believed to be an integral part of multiple myeloma (MM) treatment, the role of hematopoietic stem-cell transplantation (HSCT) is being challenged.As such, we sought to evaluate the impact of HSCT in the era of novel agents.Methods: A multicenter, retrospective, longitudinal cohort study was carried out between January 201